Chronic diarrhea in an HIV patient: gastrointestinal involvement by histoplasma capsulatum.

Abstract

Histoplasmosis is a systemic granulomatous mycosis caused by Histoplasma capsulatum, primarily affecting immunocompromised patients. Its gastrointestinal presentation is rare and can mimic other infectious or inflammatory colitides, making diagnosis challenging and delaying early treatment.

We present the case of a 26-year-old male with a history of HIV infection who sought medical attention due to chronic diarrhea lasting several months. He was ultimately diagnosed with intestinal histoplasmosis, as biopsies revealed granulomatous duodenitis and ileocolitis with the presence of Histoplasma capsulatum.

Keywords: chronic diarrhea, histoplasmosis, HIV infection.